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Article

Quantitative and functional evaluation of innate immune responses in patients with common variable immunodeficiency.

Journal of investigational allergology & clinical immunology - 1 Jan 2011

Trujillo C M, Muskus C, Arango J, Patiño P J, Montoya C J

Abstract excerpt

OBJECTIVES: We evaluate the frequency and functional response of innate immune cells in peripheral blood (PB) from patients with common variable immunodeficiency (CVID) and healthy controls upon activation with agonists of the Toll-like receptors (TLR) TLR2, TLR4, and TLR9. In addition, several nonsynonymous single nucleotide polymorphisms (SNPs) within these TLR genes were examined. METHODS: Flow cytometry was...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21548449

Genes

TLR2
TLR4
TLR9
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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