Article
Distribution of lymphocyte subpopulations in patients with polycythemia vera.
Human immunology - 1 Jun 2015
Sanchez Carole, Le Treut Thérèse, Baier Céline, Sébahoun Gérard, Costello Régis T
Abstract excerpt
Polycythemia vera (PV) is a disease with slow development. Nonetheless, the immune response is unable to eliminate the uncontrolled proliferating hematopoietic cells, leading to treatment of patient by phlebotomy and/or cytotoxic drugs. In addition, a higher incidence of cancers is observed in PV patients, independently of treatment. These observations argue for an impaired immune response in PV. In order to...
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