Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fcr1p inhibits development of fluconazole resistance in Candida albicans by abolishing CDR1 induction.

Biological & pharmaceutical bulletin - 1 Jan 2007

Shen Hui, An Mao-Mao, Wang De Jun, Xu Zheng, Zhang Jun-Dong, Gao Ping-Hui, Cao Ying-Ying, Cao Yong-Bing, Jiang Yuan-Ying

Abstract excerpt

Overexpression of Candida drug resistance 1 (CDR1) gene in Candida albicans (C. albicans), an efflux pump, is one of the major mechanisms contributing to drug resistance. C. albicans for fluconazole resistance 1 protein (Fcr1p) is a member of the family of zinc cluster proteins homologous to Pdr1p and Pdr3p (pleiotropic drug resistance protein) mediating azole resistance in Saccharomyces cerevisiae (S....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Candida albicans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Candidiasis

Share to Drug Resistance, Fungal

Share to Fluconazole

Share to Fluorescent Dyes

Share to Metalloproteins

Share to Rhodamines

Source

Identifiers

PMID: 17202662
DOI: 10.1248/bpb.30.68

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fcr1p inhibits development of fluconazole resistance in Candida albicans by abolishing CDR1 induction.PMID 17202662Read ↗

Isolation of a putative Candida albicans transcriptional regulator involved in pleiotropic drug resistance by functional complementation of a pdr1 pdr3 mutation in Saccharomyces cerevisiae.Semantic proximity Read ↗

Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiaeSemantic proximity Read ↗

Drug susceptibilities of yeast cells are affected when expressing mutant Candida albicans drug resistance protein.Semantic proximity Read ↗

Candida glabrata PDR1 , a Transcriptional Regulator of a Pleiotropic Drug Resistance Network, Mediates Azole Resistance in Clinical Isolates and Petite MutantsSemantic proximity Read ↗

Efflux-mediated resistance to fluconazole could be modulated by sterol homeostasis in Saccharomyces cerevisiae.Semantic proximity Read ↗

An update on antifungal targets and mechanisms of resistance in Candida albicans.Semantic proximity Read ↗

TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2.Semantic proximity Read ↗

The TAC1 Gene in Candida albicans: Structure, Function, and Role in Azole Resistance: A Mini-Review.Semantic proximity Read ↗

A novel multidrug efflux transporter gene of the major facilitator superfamily from Candida albicans (FLU1) conferring resistance to fluconazoleSemantic proximity Read ↗

STB5 is a negative regulator of azole resistance in Candida glabrata.Semantic proximity Read ↗

Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals.Semantic proximity Read ↗

Participation of the ABC Transporter CDR1 in Azole Resistance of Candida lusitaniaeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.