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Article

An update on antifungal targets and mechanisms of resistance in Candida albicans.

Medical mycology - 1 Jun 2005

Akins Robert A

Abstract excerpt

Much progress has been made in the last decade in identifying genes responsible for antifungal resistance in Candida albicans. Attention has focused on five major C. albicans genes: ABC transporter genes CDR1 and CDR2, major facilitator efflux gene MDR1, and ergosterol biosynthesis genes ERG11 and ERG3. Resistance involves mutations in 14C-lanosterol demethylase, targeted by fluconazole (FLZ) and encoded by...

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Source

Identifiers

PMID: 16110776
DOI: 10.1080/13693780500138971

Genes

CDR2
ERG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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