Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans.

PloS one - 28 Dec 2010

Chotard Laëtitia, Skorobogata Olga, Sylvain Marc-André, Shrivastava Sanhita, Rocheleau Christian E

Abstract excerpt

C. elegans first stage (L1) larvae hatched in the absence of food, arrest development and enter an L1 diapause, whereby they can survive starvation for several weeks. The physiological and metabolic requirements for survival during L1 diapause are poorly understood. However, yolk, a cholesterol binding/transport protein, has been suggested to serve as an energy source. Here, we demonstrate that C. elegans TBC-2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amines
Share to Caenorhabditis elegans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caenorhabditis elegans Proteins

Share to Cholesterol

Share to Endosomes

Share to GTPase-Activating Proteins

Share to Lysosomes

Source

Open in PubMed Open full text

Identifiers

PMID: 21203392
DOI: 10.1371/journal.pone.0015662
PMCID: PMC3011002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TBC-2 is required for embryonic yolk protein storage and larval survival during L1 diapause in Caenorhabditis elegans.PMID 21203392Read ↗

Cathepsin L protease (CPL-1) is essential for yolk processing during embryogenesis in Caenorhabditis elegans.Semantic proximity Read ↗

New genetic regulators question relevance of abundant yolk protein production in C. elegans.Semantic proximity Read ↗

Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte.Semantic proximity Read ↗

Guidelines for monitoring autophagy in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5.Semantic proximity Read ↗

Function of the Caenorhabditis elegans ABC transporter PGP-2 in the biogenesis of a lysosome-related fat storage organelle.Semantic proximity Read ↗

Yolk-deprived Caenorhabditis elegans secure brood size at the expense of competitive fitness.Semantic proximity Read ↗

CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans.Semantic proximity Read ↗

The C. elegans P4-ATPase TAT-1 regulates lysosome biogenesis and endocytosis.Semantic proximity Read ↗

Multiple roles of endocytosis and autophagy in intracellular remodeling during oocyte-to-embryo transitionSemantic proximity Read ↗

Role of autophagy in Caenorhabditis elegansSemantic proximity Read ↗

TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.