Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat

1 Jan 2007

Abstract excerpt

Viral infections are associated epidemiologically with the expression of type 1 diabetes in humans, but the mechanisms underlying this putative association are unknown. To investigate the role of viruses in diabetes, we used a model of viral induction of autoimmune diabetes in genetically susceptible biobreeding diabetes-resistant (BBDR) rats. BBDR rats do not develop diabetes in viral-Ab-free environments, but...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Immune Response and Inflammation
Share to Influenza Virus Research Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17202329
DOI: 10.4049/jimmunol.178.2.693

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant RatPMID 17202329Read ↗

Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations.Semantic proximity Read ↗

The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.Semantic proximity Read ↗

The Role of Toll-Like Receptor Pathways in the Mechanism of Type 1 DiabetesSemantic proximity Read ↗

Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex.Semantic proximity Read ↗

Infection of peripancreatic lymph nodes but not islets precedes Kilham rat virus-induced diabetes in BB/Wor ratsSemantic proximity Read ↗

Viral infections as potential triggers of type 1 diabetes.Semantic proximity Read ↗

Lessons on autoimmune diabetes from animal models.Semantic proximity Read ↗

Closing the circle between the bedside and the bench: Toll-like receptors in models of virally induced diabetes.Semantic proximity Read ↗

Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanismsSemantic proximity Read ↗

Genetic Susceptibility of the Host in Virus-Induced DiabetesSemantic proximity Read ↗

Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus.Semantic proximity Read ↗

Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.