Article
Closing the circle between the bedside and the bench: Toll-like receptors in models of virally induced diabetes.
Annals of the New York Academy of Sciences - 1 Dec 2008
Bortell Rita, Pino Steven C, Greiner Dale L, Zipris Danny, Rossini Aldo A
Abstract excerpt
Animal models provide many strategies to unravel the complex interplay of genetic, immunologic, and environmental factors involved in the pathogenesis of type 1A (autoimmune) diabetes. Diabetes can be studied at multiple levels, and new technological advancements provide insights into the functioning of organelle and cellular structures. The role of innate immunity in the response to environmental pathogens has...
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