Article
Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat.
Diabetes - 1 Oct 2010
Kaldunski Mary, Jia Shuang, Geoffrey Rhonda, Basken Joel, Prosser Simon, Kansra Sanjay, Mordes John P, Lernmark Ake, Wang Xujing, Hessner Martin J
Abstract excerpt
OBJECTIVE: Inflammatory mediators associated with type 1 diabetes are dilute and difficult to measure in the periphery, necessitating development of more sensitive and informative biomarkers for studying diabetogenic mechanisms, assessing preonset risk, and monitoring therapeutic interventions. RESEARCH DESIGN AND METHODS: We previously utilized a novel bioassay in which human type 1 diabetes sera were used to...
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