Article
[Relationship of the curative effects of gefitinib on non-small cell lung carcinoma to gender and to epithelial growth factor receptor status].
Zhonghua yi xue za zhi - 10 Oct 2006
Xu Chong-rui, Lin Jia-ying, Wang Zhen, Zhou Qing, Zhang Guo-chun, Wang Kun, Yang Xue-ning, Chen Gang, Yang Jin-ji, Huang Yu-juan, Liao Ri-qiang, Wu Yi-long
Abstract excerpt
OBJECTIVE: To investigate the mutation of epithelial growth factor receptor (EGFR) gene in the non-small cell lung carcinoma (LSCLG) patients with different genders and the relationship between the gender of LSCLG patients and the curative effects of gefitinib, an specific tyrosine kinase. METHODS: Tumor specimens were obtained from 135 NSCLC patients, 94 males (78.7% smoking) and 41 females (17.1% smoking), of...
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