Article
[Establishment of a model to assess the clinical efficacy of Gefitinib in treatment of non-small cell lung cancer].
Zhonghua yi xue za zhi - 20 Nov 2007
Wang Yan, Zhang Xiang-Ru, Zhu Hong-Xia, Wang Bin, Xu Ning-Zhi, Sun Yan
Abstract excerpt
OBJECTIVE: To establish a model to predict the clinical response of Gefitinib in non-small cell lung cancer (NSCLC). METHODS: The clinical outcomes of 262 consecutive advanced NSCLC patients to oral treatment of gefitinib 250 mg daily in the past 4 years were reviewed. DNA sequencing was used to detect the mutations in the exons 18, 19, 20, and 21 of the epidermal growth factor receptor (EGFR) tyrosine kinase...
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