Article
Epidermal growth factor receptor mutations and the clinical outcome in male smokers with squamous cell carcinoma of lung.
Journal of Korean medical science - 1 Jun 2009
Park Se Hoon, Ha Seung Yeon, Lee Jae-Ik, Lee Hyewon, Sim Hoyong, Kim Young Saing, Hong Junshik, Park Jinny, Cho Eun Kyung, Shin Dong Bok, Lee Jae Hoon
Abstract excerpt
Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) have been reported to be related to certain clinical characteristics (i.e., female, non-smokers with adenocarcinoma) and gefitinib responsiveness. This exploratory analysis was performed to determine the incidence of EGFR mutations in male smokers with squamous cell carcinoma, who were treated with EGFR tyrosine kinase...
Topics
- Adult
- Aged
- Antineoplastic Agents
- Carcinoma, Non-Small-Cell Lung
- ErbB Receptors
- Gefitinib
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Protein Kinase Inhibitors
- Quinazolines