Article
Sensitivity to epidermal growth factor receptor tyrosine kinase inhibitors in males, smokers, and non-adenocarcinoma lung cancer in patients with EGFR mutations.
The International journal of biological markers - 27 Sept 2013
Zeng Zhu, Chen Hua-Jun, Yan Hong-Hong, Yang Jin-Ji, Zhang Xu-Chao, Wu Yi-Long
Abstract excerpt
INTRODUCTION: The demographical/clinical characteristics of being Asian, having an adenocarcinoma, being female, and being a "never-smoker" are regarded as favorable predictors for epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) efficacy in non-small cell lung cancer (NSCLC) with unknown EGFR gene status. In this study, we examined the effects of the supposedly unfavorable clinical...
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