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Article

A strong genetic determinant of hyperoxia-related retinal degeneration on mouse chromosome 6.

Investigative ophthalmology & visual science - 1 Jan 2007

Smit-McBride Zeljka, Oltjen Sharon L, Lavail Matthew M, Hjelmeland Leonard M

Abstract excerpt

PURPOSE: Hyperoxia-related retinal degeneration (HRRD) is a model system in the mouse in which elevated oxygen levels are used to induce retinal degeneration. The hypothesis for the present study was that strain differences in HRRD susceptibility are due to allelic variants of one or more genes in the mouse genome whose human orthologues should be important targets for research and drug development. METHODS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17197561
DOI: 10.1167/iovs.06-0854

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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