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Article

Expression and Role of the Early-Response Gene<i>Oxr1</i>in the Hyperoxia-Challenged Mouse Retina

1 Oct 2008

Abstract excerpt

PURPOSE: To examine the response of mouse retina to sustained hyperoxia. Hyperoxia is toxic to photoreceptors after sustained exposure (7-14 days in the C57BL/6J mouse) but has been reported to enhance photoreceptor function after short-term exposure. METHODS: Retinas from the hyperoxia-vulnerable C57BL/6J mouse and from the hyperoxia-resistant BALB/cJ mouse were examined after 0, 3, 7, 14, and 35 days' exposure...

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PMID: 18539939
DOI: 10.1167/iovs.08-1722

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