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Article

A strong and highly significant QTL on chromosome 6 that protects the mouse from age-related retinal degeneration.

Investigative ophthalmology & visual science - 1 Jun 2003

Danciger Michael, Lyon Jessica, Worrill Danielle, LaVail Matthew M, Yang Haidong

Abstract excerpt

PURPOSE: BALB/cByJ (C) albino mice have significantly more retinal degeneration as they age than C57BL/6J-c(2J) (B6) albinos. To discover the genetic loci that influence age-related retinal degeneration (ARD), a quantitative genetics study was performed with 8-month-old progeny from an intercross between these two strains. METHODS: The thickness of the outer nuclear layer of the retina was used as the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mice, Inbred BALB C

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Source

Identifiers

PMID: 12766041
DOI: 10.1167/iovs.02-1252

Genes

RPE65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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