Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leads from xenobiotic metabolism genes for Parkinson's disease among north Indians.

Pharmacogenetics and genomics - 1 Dec 2011

Punia Sohan, Das Mitashree, Behari Madhuri, Dihana Maninder, Govindappa Shyla T, Muthane Uday B, Thelma B K, Juyal Ramesh C

Abstract excerpt

OBJECTIVE: Pesticide/neurotoxin/free radical-induced oxidative stress leading to dopaminergic neuronal vulnerability is known to promote sporadic Parkinson's disease (PD). This study investigated the contribution of polymorphisms in genes from drug-metabolizing enzymes (DMEs) and the oxidative stress pathway to PD susceptibility and severity among a north Indian cohort. METHODS: Three hundred and thirty-nine PD...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arylamine N-Acetyltransferase
Share to Aryldialkylphosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cohort Studies

Share to Gene-Environment Interaction

Share to NAD(P)H Dehydrogenase (Quinone)

Share to Parkinson Disease

Share to Xenobiotics

Source

Identifiers

PMID: 22016051
DOI: 10.1097/FPC.0b013e32834bcd74

Genes

NQO1
PON2
GSTO1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leads from xenobiotic metabolism genes for Parkinson's disease among north Indians.PMID 22016051Read ↗

Parkinson's disease and pesticides: A meta-analysis of disease connection and genetic alterations.Semantic proximity Read ↗

Pesticide exposure on southwestern Taiwanese with MnSOD and NQO1 polymorphisms is associated with increased risk of Parkinson's disease.Semantic proximity Read ↗

Genomic and pharmacogenomic biomarkers of Parkinson's disease.Semantic proximity Read ↗

Environmental-Genetic Interactions in the Pathogenesis of Parkinson's DiseaseSemantic proximity Read ↗

Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene-Pesticide Interactions in a Case-Control Study of Parkinson's Disease, California (USA).Semantic proximity Read ↗

OXPHOS toxicogenomics and Parkinson's disease.Semantic proximity Read ↗

An association between idiopathic Parkinson's disease and polymorphisms of phase II detoxification enzymes: glutathione S-transferase M1 and quinone oxidoreductase 1 and 2.Semantic proximity Read ↗

Nutrigenomics in Parkinson's disease: diversity of modulatory actions of polyphenols on epigenetic effects induced by toxins.Semantic proximity Read ↗

Role of PON1 L55M Gene Polymorphism in Parkinson's Disease among North Indian Population.Semantic proximity Read ↗

Genetic profile for the detection of susceptibility to poisoning by exposure to pesticides.Semantic proximity Read ↗

Genetic variants in xenobiotic detoxification enzymes, antioxidant defenses and hormonal pathways as biomarkers of susceptibility to prostate cancer.Semantic proximity Read ↗

Cytochrome P450 2E1 gene polymorphisms/haplotypes and Parkinson's disease in a Swedish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.