Article
Screening of 134 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes replicates association with 12 SNPs in nine genes.
Diabetes - 1 Jan 2007
Willer Cristen J, Bonnycastle Lori L, Conneely Karen N, Duren William L, Jackson Anne U, Scott Laura J, Narisu Narisu, Chines Peter S, Skol Andrew, Stringham Heather M, Petrie John, Erdos Michael R, Swift Amy J, Enloe Sareena T, Sprau Andrew G, Smith Eboni, Tong Maurine, Doheny Kimberly F, Pugh Elizabeth W, Watanabe Richard M, Buchanan Thomas A, Valle Timo T, Bergman Richard N, Tuomilehto Jaakko, Mohlke Karen L, Collins Francis S, Boehnke Michael
Abstract excerpt
More than 120 published reports have described associations between single nucleotide polymorphisms (SNPs) and type 2 diabetes. However, multiple studies of the same variant have often been discordant. From a literature search, we identified previously reported type 2 diabetes-associated SNPs. We initially genotyped 134 SNPs on 786 index case subjects from type 2 diabetes families and 617 control subjects with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.