Article
Association analysis of type 2 diabetes Loci in type 1 diabetes.
Diabetes - 1 Jul 2008
Qu Hui-Qi, Grant Struan F A, Bradfield Jonathan P, Kim Cecilia, Frackelton Edward, Hakonarson Hakon, Polychronakos Constantin
Abstract excerpt
OBJECTIVE: To search for a possible association of type 1 diabetes with 10 validated type 2 diabetes loci, i.e., PPARG, KCNJ11, WFS1, HNF1B, IDE/HHEX, SLC30A8, CDKAL1, CDKN2A/B, IGF2BP2, and FTO/RPGRIP1L. RESEARCH DESIGN AND METHODS: Two European population samples were studied: 1) one case-control cohort of 514 type 1 diabetic subjects and 2,027 control subjects and 2) one family cohort of 483 complete type 1...
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