Article
Genome-wide association studies and type 2 diabetes.
Briefings in functional genomics - 1 Mar 2011
Wheeler Eleanor, Barroso Inês
Abstract excerpt
In recent years, the search for genetic determinants of type 2 diabetes (T2D) has changed dramatically. Although linkage and small-scale candidate gene studies were highly successful in the identification of genes, which, when mutated, caused monogenic forms of T2D, they were largely unsuccessful when applied to the more common forms of the disease. To date, these approaches have only identified two loci (PPARG,...
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