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Article

A new era in finding Type 2 diabetes genes-the unusual suspects.

Diabetic medicine : a journal of the British Diabetic Association - 1 Jul 2007

Frayling T M

Abstract excerpt

In 1988 the task of identifying Type 2 diabetes genes was described as a nightmare. For the next 17 years this proved to be largely correct. In the meantime the prevalence of Type 2 diabetes rose sharply due to non-genetic factors, compounding the problem of trying to find genes. Despite a huge amount of effort, progress was disappointing and only two genes, PPARG and KCNJ11, were confirmed beyond doubt as Type 2...

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Share to Diabetes Mellitus, Type 2
Share to PPARG gene
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Multifactorial Inheritance

Share to Polymorphism, Genetic

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Share to TCF Transcription Factors

Share to Transcription Factor 7-Like 2 Protein

Source

Identifiers

PMID: 17561964
DOI: 10.1111/j.1464-5491.2007.02172.x

Genes

KCNJ11
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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