Article
Distribution of 1298A>C polymorphism of methylenetetrahydrofolate reductase gene in patients with bipolar disorder and schizophrenia.
European psychiatry : the journal of the Association of European Psychiatrists - 1 Jan 2007
Kempisty Bartosz, Bober Anna, Łuczak Marta, Czerski Piotr, Szczepankiewicz Aleksandra, Hauser Joanna, Jagodziński Paweł P
Abstract excerpt
We investigated the genotype frequency of methylenetetrahydrofolate reductase (MTHFR) 1298A>C polymorphism in the group of patients with bipolar disorder type I (BDI) (n=200) and schizophrenia (n=200) and in the control group (n=300). Odds ratio (OR) for patients with BD and schizophrenia in 1298CC homozygous state was 3.768 (95% CI=1.752-8.104); P=0.0003; (P=0.0006 after Bonferroni correction) and 2.694; (95%...
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