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Article

Methylenetetrahydrofolate reductase (MTHFR) polymorphism susceptibility to schizophrenia and bipolar disorder: an updated meta-analysis.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Feb 2015

Hu Cai-Yun, Qian Zhen-Zhong, Gong Feng-Feng, Lu Shan-Shan, Feng Fang, Wu Yi-Le, Yang Hui-Yun, Sun Ye-Huan

Abstract excerpt

Previous studies examining the possible role of the methylenetetrahydrofolate reductase (MTHFR) polymorphisms in the development of schizophrenia (SZ) and bipolar disorder (BPD) have provided inconclusive findings, this meta-analysis was therefore designed to get a more reliable assessment. A total of 38 articles were identified through a search of electronic databases, up to 27 February 2014. Odds ratios (ORs)...

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Source

Identifiers

PMID: 24938371
DOI: 10.1007/s00702-014-1261-8

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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