Article
C677T methylenetetrahydrofolate reductase gene polymorphisms in bipolar disorder: an association study in the Chinese population and a meta-analysis of genetic association studies.
Neuroscience letters - 2 Jan 2009
Chen Zhuo, Liu Yun, Zhang Di, Liu Zhe, Wang Peng, Zhou Daizhan, Zhao Teng, Wang Ting, Xu He, Li Sheng, Feng Guoyin, He Lin, Yu Lan
Abstract excerpt
The methylenetetrahydrofolate reductase (MTHFR) gene variant C677T is suspected to be a risk factor for psychiatric disorders, but it remains uncertain whether the MTHFR C677T variant is associated with bipolar disorders. To investigate possible association, unrelated controls (n=461) with no history of psychiatric disorders and patients (n=501) diagnosed with bipolar disorder were recruited in this study. In...
Topics
- Adult
- Asian People
- Bipolar Disorder
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Meta-Analysis as Topic