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Article

MTHFD 1958G>A and MTR 2756A>G polymorphisms are associated with bipolar disorder and schizophrenia.

Psychiatric genetics - 1 Jun 2007

Kempisty Bartosz, Sikora Jacek, Lianeri Margarita, Szczepankiewicz Aleksandra, Czerski Piotr, Hauser Joanna, Jagodzinski Paweł Piotr

Abstract excerpt

BACKGROUND: The etiology of bipolar disorder (BD) and schizophrenia is very complex. Polymorphic variants of genes encoding enzymes of the monoaminergic may be involved in development of BD and schizophrenia. Therefore, we examined the prevalence of 1958G>A polymorphism of MTHFD1 gene, encoding trifunctional folate enzyme 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase...

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PMID: 17417062
DOI: 10.1097/YPG.0b013e328029826f

Genes

MTHFD1
MTR

Variants

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