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Article

Early motor development is abnormal in complexin 1 knockout mice.

Neurobiology of disease - 1 Mar 2007

Glynn Dervila, Sizemore Rachel J, Morton A Jennifer

Abstract excerpt

Complexin I expression is dysregulated in a number of neurological diseases including schizophrenia and depression. Adult complexin 1 knockout (Cplx1(-/-)) mice are severely ataxic and show deficits in exploration and emotional reactivity. Here, we evaluated early behavioural development of Cplx1(-/-) mice. Cplx1(-/-) mice showed marked abnormalities. They develop ataxia by post-natal day 7 (P7), and by P21 show...

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Identifiers

PMID: 17188502
DOI: 10.1016/j.nbd.2006.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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