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Article

Integrative hypothesis for Huntington's disease: a brief review of experimental evidence.

Physiological research - 1 Jan 2007

Perez-De La Cruz V, Santamaria A

Abstract excerpt

Huntington's disease (HD) is a demential, neurodegenerative inheritable disease affecting middle-aged patients. HD is characterized by uncontrolled choreiform movements, psychiatric symptoms and cognitive decline. Histopathological changes in HD brains reveal a considerable damage to basal ganglia, particularly affecting middle-sized spiny neurons from the caudate-putamen region. Neurochemical changes are...

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PMID: 17184144
DOI: 10.33549/physiolres.931049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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