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Article

Oxidative damage in Huntington's disease pathogenesis.

Antioxidants & redox signaling - 1 Jan 2000

Browne Susan E, Beal M Flint

Abstract excerpt

Huntington's disease (HD) is a devastating neurodegenerative disorder characterized by the progressive development of involuntary choreiform movements, cognitive impairment, neuropsychiatric symptoms, and premature death. These phenotypes reflect neuronal dysfunction and ultimately death in selected brain regions, the striatum and cerebral cortex being principal targets. The genetic mutation responsible for the...

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Identifiers

PMID: 17034350
DOI: 10.1089/ars.2006.8.2061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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