Article
A weakened transcriptional enhancer yields variegated gene expression.
PloS one - 20 Dec 2006
Collins Cathy, Azmi Peter, Berru Maribel, Zhu Xiaofu, Shulman Marc J
Abstract excerpt
Identical genes in the same cellular environment are sometimes expressed differently. In some cases, including the immunoglobulin heavy chain (IgH) locus, this type of differential gene expression has been related to the absence of a transcriptional enhancer. To gain additional information on the role of the IgH enhancer, we examined expression driven by enhancers that were merely weakened, rather than fully...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
