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Article

Enhancer requirement for histone methylation linked with gene activation.

The FEBS journal - 1 Dec 2008

Rentoft Matilda, Kim Kihoon, Cho Youngran, Lee Choon-Hwan, Kim Aeri

Abstract excerpt

Enhancers cause a high level of transcription and activation of chromatin structure at target genes. Hyperacetylation of histones H3 and H4, a mark of active chromatin, is established broadly across target loci by enhancers that function over long distances. In the present study, we studied the role of an enhancer in methylation of various lysine residues on H3 by comparing a model gene locus having an active...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19021773
DOI: 10.1111/j.1742-4658.2008.06728.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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