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Article

Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2007

Wei Ke, Che Nam, Chen Fabian

Abstract excerpt

Smooth muscle gene expression is required for the proper development and function of multiple organ systems. Expression of smooth muscle genes is critical for contractile function and tissue architectural integrity. One critical transcription factor for smooth muscle gene expression is the Serum Response Factor (SRF). SRF is expressed ubiquitously, but tissue-specific transcriptional regulation is conferred by...

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Identifiers

PMID: 17183527
DOI: 10.1002/dvdy.21041

Genes

SRF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression.PMID 17183527Read ↗

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Myocardin is sufficient and necessary for cardiac gene expression in Xenopus.Semantic proximity Read ↗

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Myocardin regulates expression of contractile genes in smooth muscle cells and is required for closure of the ductus arteriosus in mice.Semantic proximity Read ↗

The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.Semantic proximity Read ↗

Smooth muscle cell-specific transcription is regulated by nuclear localization of the myocardin-related transcription factors.Semantic proximity Read ↗

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