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Article

The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2009

Zhou Jiliang, Zhang Min, Fang Hong, El-Mounayri Omar, Rodenberg Jennifer M, Imbalzano Anthony N, Herring B Paul

Abstract excerpt

OBJECTIVE: Regulatory complexes comprising myocardin and serum response factor (SRF) are critical for the transcriptional regulation of many smooth muscle-specific genes. However, little is known about the epigenetic mechanisms that regulate the activity of these complexes. In the current study, we investigated the role of SWI/SNF ATP-dependent chromatin remodeling enzymes in regulating the myogenic activity of...

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Share to Chromatin Assembly and Disassembly
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle Development

Share to Muscle, Smooth, Vascular

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Source

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Identifiers

PMID: 19342595
DOI: 10.1161/ATVBAHA.109.187229
PMCID: PMC2730881

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.Semantic proximity Read ↗

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