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Article

Establishment of stable human fibroblast cell lines constitutively expressing active Rho-GTPases.

Protoplasma - 1 Dec 2006

Servotte S, Zhang Z, Lambert C A, Ho T T Giang, Chometon G, Eckes B, Krieg T, Lapière C M, Nusgens B V, Aumailley M

Abstract excerpt

Small GTP-binding proteins of the Rho family (RhoA, Cdc42, Rac1) regulate the organisation and the turnover of the cell's cytoskeleton and adhesion structures. A significant function of these cellular structures is to translate and counterbalance forces applied to, or generated by, cells in order to maintain homeostasis and control cell movement. We therefore hypothesised that Rho-GTPases are directly involved in...

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PMID: 17180504
DOI: 10.1007/s00709-006-0204-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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