Article
Ras superfamily monomeric G proteins in carcinoma cell motility.
Cancer letters - 28 Jan 2003
Oxford Gary, Theodorescu Dan
Abstract excerpt
With over 100 members in humans, the Ras superfamily is a diverse group of monomeric G proteins participating in many cellular processes. Members of the Ras, Rho, and Arf families have been shown to regulate cell motility in fibroblasts and epithelial cells. Ras and Rho family members are also widely involved in human tumorigenesis, either through activating mutations or by overexpression. In this review, tools...
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