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Article

Nano-mechanical properties of living cells expressing constitutively active RhoA effectors.

Biochemical and biophysical research communications - 17 Dec 2010

Tamura Kazushi, Mizutani Takeomi, Haga Hisashi, Kawabata Kazushige

Abstract excerpt

Filamentous actin and myosin-II are major determinants of cell mechanics and are tightly regulated by a small guanosine triphosphatase, RhoA, and its downstream effectors. We examined the effects of constitutively active mutants of RhoA effectors, which have not been reported before, on cortical stiffness of living cells by using scanning probe microscopy, fluorescence microscopy, and truncated mutants of RhoA...

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PMID: 21078298
DOI: 10.1016/j.bbrc.2010.11.036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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