Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells.

BioMed research international - 1 Jan 2014

Masiello Maria Grazia, Cucina Alessandra, Proietti Sara, Palombo Alessandro, Coluccia Pierpaolo, D'Anselmi Fabrizio, Dinicola Simona, Pasqualato Alessia, Morini Veronica, Bizzarri Mariano

Abstract excerpt

Microgravity exerts dramatic effects on cell morphology and functions, by disrupting cytoskeleton and adhesion structures, as well as by interfering with biochemical pathways and gene expression. Impairment of cells behavior has both practical and theoretical significance, given that investigations of mechanisms involved in microgravity-mediated effects may shed light on how biophysical constraints cooperate in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Apoptosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Cell Cycle

Share to Cell Line, Tumor

Share to Cell Survival

Share to Cytoskeletal Proteins

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 25215287
DOI: 10.1155/2014/652434
PMCID: PMC4151603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic switch induced by simulated microgravity on MDA-MB-231 breast cancer cells.PMID 25215287Read ↗

Short-term effects of simulated microgravity on morphology and gene expression in human breast cancer cells.Semantic proximity Read ↗

Long-Term Simulation of Microgravity Induces Changes in Gene Expression in Breast Cancer CellsSemantic proximity Read ↗

The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis ModelSemantic proximity Read ↗

Recent studies of the effects of microgravity on cancer cells and the development of 3D multicellular cancer spheroidsSemantic proximity Read ↗

Simulated microgravity induces HIF-1-dependent pseudohypoxic and glycolytic state in triple- negative breast cancerSemantic proximity Read ↗

Simulated Microgravity-Induced Changes to Drug Response in Cancer Cells Quantified Using Fluorescence MorphometrySemantic proximity Read ↗

Alterations of Growth and Focal Adhesion Molecules in Human Breast Cancer Cells Exposed to the Random Positioning MachineSemantic proximity Read ↗

Identifications of novel mechanisms in breast cancer cells involving duct-like multicellular spheroid formation after exposure to the Random Positioning Machine.Semantic proximity Read ↗

Microgravity-Induced Changes to Drug Response in Cancer Cells Quantified Using Fluorescence MorphometrySemantic proximity Read ↗

Microgravity, Stem Cells, and Cancer: A New Hope for Cancer TreatmentSemantic proximity Read ↗

Pathways Regulating Spheroid Formation of Human Follicular Thyroid Cancer Cells under Simulated Microgravity Conditions: A Genetic ApproachSemantic proximity Read ↗

Physical forces and non linear dynamics mould fractal cell shape: quantitative morphological parameters and cell phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.