Article
Mammalian mRNA splice-isoform selection is tightly controlled.
Genetics - 1 Mar 2007
Chisa Jennifer L, Burke David T
Abstract excerpt
Post-transcriptional RNA processing is an important regulatory control mechanism for determining the phenotype of eukaryotic cells. The processing of a transcribed RNA species into alternative splice isoforms yields products that can perform different functions. Each type of cell in a multi-cellular organism is presumed to actively control the relative quantities of alternative splice isoforms. In this study, the...
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