Article
Mapping Whole-Transcriptome Splicing in Mouse Hematopoietic Stem Cells.
Stem cell reports - 10 Jan 2017
Goldstein Oron, Meyer Karin, Greenshpan Yariv, Bujanover Nir, Feigin Mili, Ner-Gaon Hadas, Shay Tal, Gazit Roi
Abstract excerpt
Hematopoietic stem cells (HSCs) are rare cells that generate all the various types of blood and immune cells. High-quality transcriptome data have enabled the identification of significant genes for HSCs. However, most genes are expressed in various forms by alternative splicing (AS), extending transcriptome complexity. Here, we delineate AS to determine which isoforms are expressed in mouse HSCs. Our analysis of...
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