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Article

Full-length RNA transcript sequencing traces brain isoform diversity in house mouse natural populations.

Genome research - 20 Nov 2024

Zhang Wenyu, Guenther Anja, Gao Yuanxiao, Ullrich Kristian, Huettel Bruno, Ahmad Aftab, Duan Lei, Wei Kaizong, Tautz Diethard

Abstract excerpt

The ability to generate multiple RNA transcript isoforms from the same gene is a general phenomenon in eukaryotes. However, the complexity and diversity of alternative isoforms in natural populations remain largely unexplored. Using a newly developed full-length transcript enrichment protocol with 5' CAP selection, we sequenced full-length RNA transcripts of 48 individuals from outbred populations and subspecies...

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Identifiers

PMID: 39288994
DOI: 10.1101/gr.279166.124
PMCID: PMC11610456

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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