A new strategy based on recombinant viruses as a tool for assessing drug susceptibility of human immunodeficiency virus type 1.

doi:10.1002/jmv.20770

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Article

A new strategy based on recombinant viruses as a tool for assessing drug susceptibility of human immunodeficiency virus type 1.

Journal of medical virology - 1 Feb 2007

Garcia-Perez J, Sanchez-Palomino S, Perez-Olmeda M, Fernandez B, Alcami J

Abstract excerpt

The emergence of drug-resistant variants during antiretroviral therapy is a serious obstacle to sustained suppression of the human immunodeficiency virus type 1 (HIV-1). For that reason, resistance assays are essential to guide clinicians in the selection of optimal treatment regimens. Genotypic...

Topics

Animals
Anti-HIV Agents
Cloning, Molecular
Drug Resistance, Viral
Genes, Reporter
HIV Infections
HIV Protease
HIV Protease Inhibitors
HIV Reverse Transcriptase
HIV-1
Humans
Luciferases
Microbial Sensitivity Tests
Phenotype
Proviruses
Recombination, Genetic
Renilla
Reproducibility of Results

Source

Open in PubMed

Identifiers

PMID: 17177310
DOI: 10.1002/jmv.20770

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-17177310-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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