Article
A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1.
Antimicrobial agents and chemotherapy - 1 Apr 2000
Petropoulos C J, Parkin N T, Limoli K L, Lie Y S, Wrin T, Huang W, Tian H, Smith D, Winslow G A, Capon D J, Whitcomb J M
Abstract excerpt
Although combination antiretroviral therapy has resulted in a considerable improvement in the treatment of human immunodeficiency virus (HIV) type 1 (HIV-1) infection, the emergence of resistant virus is a significant obstacle to the effective management of HIV infection and AIDS. We have developed a novel phenotypic drug susceptibility assay that may be useful in guiding therapy and improving long-term...
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