Article
Rapid, phenotypic HIV-1 drug sensitivity assay for protease and reverse transcriptase inhibitors.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Jun 1999
Walter H, Schmidt B, Korn K, Vandamme A M, Harrer T, Uberla K
Abstract excerpt
BACKGROUND: Development of drug resistance is one of the major reasons for the failure of antiretroviral therapy of HIV-1 infection. Knowing the drug sensitivity-resistance profile of viruses present in a patient prior to treatment or change in treatment could help to optimize therapy. OBJECTIVE: Development of a rapid standardized phenotypic HIV-1 drug sensitivity assay for protease (PR) and reverse...
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