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Article

The association between mannose-binding lectin gene polymorphism and rheumatic heart disease.

Human immunology - 1 Dec 2006

Messias Reason Iara Jose, Schafranski Marcelo Derbi, Jensenius Jens Christian, Steffensen Rudi

Abstract excerpt

Mannan-binding lectin (MBL) is an innate pattern recognition molecule known to play a key role in pathogen clearance. As MBL2 gene polymorphism is associated to an increased susceptibility to infection, we aimed to determine genetic variations in the MBL2 gene in rheumatic heart disease (RHD). Genetic variations in the promoter and exon 1 region of the MBL2 gene were analyzed in 107 patients with RHD and 105...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17174748
DOI: 10.1016/j.humimm.2006.08.296

Genes

RHD
MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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