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Article

Association of mannose-binding lectin gene polymorphism but not of mannose-binding serine protease 2 with chronic severe aortic regurgitation of rheumatic etiology.

Clinical and vaccine immunology : CVI - 1 Jun 2008

Ramasawmy Rajendranath, Spina Guilherme S, Fae Kellen C, Pereira Alexandre C, Nisihara Renato, Messias Reason Iara Jose, Grinberg Max, Tarasoutchi Flavio, Kalil Jorge, Guilherme Luiza

Abstract excerpt

N-Acetylglucosamine (GlcNAc) is the major immunoepitope of group A streptococcal cell wall carbohydrates. Antistreptococcal antibodies cross-reactive with anti-GlcNAc and laminin are present in sera of patients with rheumatic fever. The cross-reactivity of these antibodies with human heart valvul...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18400978
DOI: 10.1128/CVI.00324-07
PMCID: PMC2446618

Genes

MBL2
MASP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18400978-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of mannose-binding lectin gene polymorphism but not of mannose-binding serine protease 2 with chronic severe aortic regurgitation of rheumatic etiology.PMID 18400978Read ↗

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