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Article

MBL2 gene polymorphism rs1800450 and rheumatic fever with and without rheumatic heart disease: an Egyptian pilot study.

Pediatric rheumatology online journal - 13 Apr 2018

Gomaa Maher Hassan, Ali Shawkey Sadik, Fattouh Aya Mohamed, Hamza Hala Salah, Badr Mohamed Mohamed

Abstract excerpt

BACKGROUND: Rheumatic fever (RF) is the result of an autoimmune response to pharyngitis caused by infection with Streptococcus pyogenes. RF is most prevalent in Africa and the Middle East. Rheumatic heart disease (RHD) is the most serious complication of RF. Mannose-binding lectin 2 gene (MBL2) has been reported to be correlated with different cardiac conditions. In Egyptian patients as a new studied ethnic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29653582
DOI: 10.1186/s12969-018-0245-x
PMCID: PMC5899397

Genes

RHD
MBL2
CRP

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