Article
MBL2 and FCN2 gene polymorphisms in a cohort of Italian children with rheumatic fever: A case-control study.
Seminars in arthritis and rheumatism - 1 Oct 2017
Marzetti Valentina, Di Battista Caterina, Ferrante Rossella, Carlucci Leonardo, Balsamo Michela, Stuppia Liborio, Lapergola Giuseppe, Antonucci Ivana, Chiarelli Francesco, Breda Luciana
Abstract excerpt
BACKGROUND: Mannose-binding lectins and human ficolins are pattern-recognition proteins involved in innate immunity. A role for MBL2 and FCN2 gene polymorphisms in the pathogenesis of recurrent severe streptococcal infections and rheumatic carditis has been suggested. OBJECTIVES: The aim of this study is to evaluate the presence of MBL2 and FCN2 gene polymorphisms (SNPs) in children with a history of rheumatic...
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