Article
Hammerhead ribozyme-based target discovery.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Sano Masayuki, Taira Kazunari
Abstract excerpt
With the accumulation of vast amounts of data as a result of the sequencing of the human genome, it is necessary to identify human genes that are involved in various cellular, developmental, and disease-related processes and to clarify their functions and potential utility as targets in the treatment of disease. Identification methods based on the use of hammerhead and hairpin ribozymes have received increasing...
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