Article
Functional gene-discovery systems based on libraries of hammerhead and hairpin ribozymes and short hairpin RNAs.
Molecular bioSystems - 1 May 2005
Sano Masayuki, Kato Yoshio, Taira Kazunari
Abstract excerpt
Abundant information about the nucleotide sequence of the human genome has become readily available and it is now necessary to develop methods for the identification of genes that are involved in important cellular, developmental and disease-related processes. Identification methods based on the activities of hammerhead and hairpin ribozymes and of short hairpin RNAs (shRNAs), whose target specificities are...
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