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Article

Ribozymes as therapeutic tools for genetic disease.

Human molecular genetics - 1 Jan 1998

Phylactou L A, Kilpatrick M W, Wood M J

Abstract excerpt

The discovery that RNA can act as a biological catalyst, as well as a genetic molecule, indicated that there was a time when biological reactions were catalysed in the absence of protein-based enzymes. It also provided the platform to develop those catalytic RNA molecules, called ribozymes, as trans -acting tools for RNA manipulation. Viral diseases or diseases due to genetic lesions could be targeted...

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Identifiers

PMID: 9735387
DOI: 10.1093/hmg/7.10.1649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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