Article
Genome-wide linkage analysis of Swedish families to identify putative susceptibility loci for cutaneous malignant melanoma.
Genes, chromosomes & cancer - 1 Dec 2011
Höiom Veronica, Tuominen Rainer, Hansson Johan
Abstract excerpt
Cutaneous malignant melanoma is a clinically and genetically heterogeneous disorder which is caused by an interaction between hereditary and environmental factors. In Sweden, a small portion of the inherited susceptibility is explained by the presence of germline mutations in the tumor suppressor gene CDKN2A. But still, the genetic background of melanoma susceptibility is largely unknown. Here, we conducted a...
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