Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach

14 Dec 2006

Abstract excerpt

Polyploidization is a part of the normal developmental process leading to platelet production during megakaryocyte (MK) differentiation. Ploidization is mainly involved in cell enlargement, but it is not clear whether gene expression is modified during MK ploidization. In this study, human MKs were grown from CD34(+) cells in the presence of thrombopoietin and sorted according to their ploidy level. A pangenomic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glycosylation and Glycoproteins Research
Share to Platelet Disorders and Treatments
Share to Proteoglycans and glycosaminoglycans research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17170127
DOI: 10.1182/blood-2006-07-037838

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approachPMID 17170127Read ↗

Transcriptional characterization of human megakaryocyte polyploidization and lineage commitmentSemantic proximity Read ↗

Megakaryocyte polyploidization: role in platelet productionSemantic proximity Read ↗

Normal and malignant megakaryopoiesisSemantic proximity Read ↗

Nicotinamide (vitamin B3) increases the polyploidisation and proplatelet formation of cultured primary human megakaryocytesSemantic proximity Read ↗

Roads to polyploidy: The megakaryocyte exampleSemantic proximity Read ↗

Megakaryocyte polyploidization is associated with a functional gene amplification.Semantic proximity Read ↗

The genomic and proteomic blueprint of mouse megakaryocytes derived from embryonic stem cells.Semantic proximity Read ↗

Single cell transcriptional characterization of human megakaryocyte lineage commitment and maturationSemantic proximity Read ↗

Characterization of Cellular Heterogeneity and an Immune Subpopulation of Human MegakaryocytesSemantic proximity Read ↗

Gene Expression Profile of Megakaryocytes from Human Cord Blood CD34+ Cells Ex Vivo Expanded by ThrombopoietinSemantic proximity Read ↗

Gene expression profiling of normal and malignant CD34-derived megakaryocytic cellsSemantic proximity Read ↗

A survey of the signaling pathways involved in megakaryocytic differentiation of the human K562 leukemia cell line by molecular and c-DNA array analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.